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Furazolidone Tablets
Dosage
Packaging
What is Furazolidone?
Active Ingredients: Furazolidone
Furazolidone Tablets are an antibiotic drug used to prevent and treat bacterial and protozoan infections. It is effective against infections such as bacterial and protozoal enteritis and urinary tract infections, salmonellosis and E. coli infections in pigs, dogs, cats, calves, and poultry, and coccidiosis and giardiasis in birds and poultry.
Furazolidone is classified as a nitrofuran antibiotic. It works by interfering with the enzyme system of bacteria, but the mechanism of action against protozoa isn't well understood. This drug shows efficiency towards certain strains of Giardia, Vibrio cholerae, Trichomonas, Coccidia, and many strains of E. coli, Enterobacter, Campylobacter, Salmonella, and Shigella.
Nitrofurans inhibit several microbial enzyme systems involved in carbohydrate metabolism and block the initiation of translation, but their exact mechanism of action remains unclear.
They have a bacteriostatic effect, that becomes bactericidal at high doses. Nitrofurans demonstrate increased activity in acidic environments, with optimal effectiveness at a pH of 5.5. Resistant mutants are uncommon, and clinical resistance develops slowly. Nitrofurans have complete cross-resistance among themselves but do not show resistance to other antibacterial agents.
Due to their limited water solubility, nitrofurans are typically administered orally. They lack systemic effectiveness, either remaining unabsorbed from the gastrointestinal tract or being rapidly eliminated, achieving inhibitory concentrations primarily in the urine.
Since Furazolidone is a Nitrofuran antibiotic, its use in food animals is currently prohibited by the FDA under the Animal Medicinal Drug Use Clarification Act of 1994.
It is important to note Furazolidone Tablets are for veterinary purposes only.
Furazolidone Tablets are a GMP-certified product that has been manufactured by AdvaCare Pharma, a pharmaceutical company specializing in global distribution. Our wide range of over 150 veterinary products is produced in facilities across China, India, and the United States.
Why choose us as your Furazolidone manufacturer?
Furazolidone Tablets, manufactured and globally supplied by AdvaCare Pharma, are one of our 250+ veterinary medicines. From supply chain coordination to product registration support, our professional teams of specialists and experts provide our veterinary distributors unparalleled support. As a trusted Furazolidone manufacturer, veterinarians and farmers alike rely on our high-quality veterinary tablets manufactured according to GMP standards.
Uses
What is Furazolidone used for?
It is used to treat enteric infections, such as:
- amebic colitis
- coccidiosis
- entamoebiasis
- Giardia infections
- Cystoisospora infections
What animals can be treated with Furazolidone Tablets?
This medicine is recommended for ornamental birds, cows, cats, dogs, and pigs.
How are Furazolidone Tablets used?
This medicine has been manufactured as a tablet, which is intended to be given orally to an animal.
How do Furazolidone Tablets help in cases of amebic colitis?
This drug can help in treating bloody diarrhea, prevent the further spreading of the disease, and can maintain the overall health of the animal.
Are only Furazolidone Tablets enough for treating amebic colitis?
The treatment of this protozoan disease should include antiprotozoal treatment and fluid therapy. It is recommended to be treated with Furazolidone (2-4mg/kg every 8 hours for 1 week). The treatment should also include metronidazole but the dog can continue shedding the trophozoites after the treatment. To treat severe colitis and diarrhea, IV fluid therapy is alsorecommended.
How can Furazolidone Tablets help in the treatment of coccidiasis?
This drug can reduce the incidence of diarrhea in animals and can prevent the further invasion of the parasite. The treatment should also include stress reduction, providing the animals with good-quality feeds and nonstressful environments. The infected animals should be moved to new areas and prevent overcrowding.
How can Furazolidine Tablets help in the treatment of Giardiasis?
Furazolidone can improve the stool of the animal. Giardiasis in dogs leads to foul-smelling diarrhea and this disease can lead to weight loss, chronic intermittent diarrhea, and fatty stool. A proper diet should also be included for animals that are infected with this disease. Patients should consume a highly digestible diet and all animals that were infected need to be re-tested 2-4 weeks after completion of treatment. The feces contains Giardia cysts and it should be immediately removed and disposed of. The infected animals also need to be bathed regularly to remove the cysts.
Can Furazolidone Tablets be used for treating viral infections?
No, Furazolidone should only be used for treating bacterial or protozoan infections. For treating viral infections, antiviral drugs, supplements, and vitamins need to be included.
Can Furazolidone Tablets be used for treating respiratory infections?
This medication should be mainly used for treating enteric infections and urinary tract infections. For successful treatment of respiratory infections, other drugs should be used that will lead to a more successful outcome.
What should be done if there are no improvements during the treatment?
The treatment is scheduled based on the current health condition of the animal and its age. If owners do not notice any improvement, it should be reported to a veterinarian. The animal should be re-examined and then it should be decided about the further treatment.
Can other drugs and supplements be given to the animals during the treatment with Furazolidone?
This should be discussed with a veterinarian prior to giving the drugs and supplements. Some drugs and supplements might interact with this medication and reduce its effectiveness.
What should be done if some side effects occur?
Furazolidone is generally safe, but every medication might lead to side effects. If owners notice any side effects, it should be reported to a veterinarian and the side effects need to be treated and managed adequately.
How should Furazolidone Tablets be stored?
This medication should be stored in a dark, dry location under 30°C. Keep the tablets in the blister pack when not in use.
Dosage
How much Furazolidone should be given to dogs?
For amebic colitis or entamebiasis, the usual dose is 2.2mg per kg of body weight, given every 8 hours for 7 days.
For coccidiosis or Cystoisospora infection, the usual dose is 8-20mg per kg, given once per week.
For Giardia infection, the usual dose is 4mg per kg of body weight, given twice per day for 7 days.
How much Furazolidone should be given to cats?
The usual dose is 4mg per kg of body weight, given twice per day for 7 days.
For coccidiosis or Cystoisospora infection, it is recommended to give 8-20mg per kg bw, given twice per day for 5 days.
How much Furazolidone should be given to horses?
The usual dose is 4mg per kg of body weight given 3 times per day.
Refer to a veterinary doctor or pharmacist for guidelines on dosage. The dosage should be determined based on the current disease, the animal's overall health, weight, and age.
Side Effects
As with all pharmaceuticals, some unwanted effects can occur from the use of Furazolidone Tablets.
Side effects are generally mild and may include diarrhea, loose stools, vomiting, and fatigue. This medication may darken urine, as well. Serious side effects may include allergy or hypersensitivity reactions.
Toxic effects from excessive nitrofuran doses include CNS symptoms (excitement, tremors, convulsions, peripheral neuritis), gastrointestinal disturbances, poor weight gain, depression of spermatogenesis, and various hypersensitivity reactions. Some nitrofurans are also known to be carcinogenic, raising concerns about their future use.
If any side effects arise, it should be reported to a veterinary professional as soon as possible.
For a comprehensive list of all possible side effects of this medication, consult a veterinarian.
Precautions
Do NOT use Furazolidone Tablets for an animal that:
- has a known allergy or hypersensitivity to any of the ingredients.
- is intended for human consumption.
There are known interactions between Furazolidone and other drugs, including alcohol, amitraz, buspirone, selegiline, sympathomimetic amines, tricyclic antidepressants, and fish or poultry with a high tyramine content.
This drug may cause a false positive on a cupric sulfate solution test.
Common side effects include gastrointestinal issues such as vomiting, diarrhea, or abdominal pain. Allergic reactions may manifest as itching, hives, swelling, or difficulty breathing. This drug should not be administered if the animal is sensitive to it. If any side effects arise, it should be reported to a veterinarian as soon as possible. Owners should observe the animals when they start treating the animals with any drug.
This drug should be kept out of reach of children and pets.
What are the most common animals Furazolidone Tablets are used for?
Furazolidone Tablets are mainly used for treating and preventing bacterial and protozoan infections. It is also effective against bacterial and protozoal enteritis, urinary tract infections, salmonellosis, and E.coli infections.
Companion Animals Infections
This drug is used for treating urinary tract infections caused by E. coli, and can be used for infections in the gastrointestinal tract. It is also effective in treating protozoal enteritis.
Poultry Infections
This drug in poultry is used for treating coccidiosis and giardiasis.
Cattle Infections
In cattle, Furazolidone is used for treating various bacterial and protozoan infections. It also includes urinary tract infections and infections caused by E. coli and Salmonella.
Pig Infections
In pigs, this medication can be used for treating various infections in the gastrointestinal or urinary tract.
Veterinarians should examine the animal before including this drug. The drug should only be included if the pathogen is susceptible to it.
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