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Fosfomycin Oral Solution
Dosage
Packaging
What is Fosfomycin Oral Solution?
Active Ingredients: Fosfomycin
Fosfomycin Oral Solution is an antibiotic drug used to treat certain bacterial infections in poultry. It is indicated for infectious coryza, fowl cholera, fowl typhoid, salmonellosis, ORT, and CRD. This formulation is considered a non-toxic, highly effective treatment for colibacillosis in broiler chickens.
Fosfomycin is a broad-spectrum phosphonic antibiotic, which works by inactivating the enzyme, enolpyruvyl transferase. This action inhibits cell wall synthesis. Fosfomycin shows bactericidal activity against gram-positive and gram-negative bacteria, such as some strains of Escherichia Coli and Salmonella.
While primarily used in poultry, the drug also finds applications in other veterinary contexts. It is sometimes used to treat urinary tract infections in companion animals, like cats and dogs. The drug's mechanism of action remains consistent across species, targeting the bacterial cell wall synthesis, although dosages and administration guidelines differ significantly based on the species, size, and specific health needs of the animal.
AdvaCare Pharma is a GMP-certified manufacturer and exporter of Fosfomycin Oral Solution worldwide. This medication is produced in our facilities located in China, India, and the USA. Our facilities are regularly inspected to ensure our products meet quality and safety standards.
Why are we a quality Fosfomycin manufacturer?
AdvaCare Pharma, an American company, is a quality manufacturer of Fosfomycin Oral Solution for veterinary use. We are committed to the manufacture and global distribution of over 250 GMP-certified veterinary medicines, including 70+ oral liquid formulations.
As a trusted Fosfomycin manufacturer, our approach to supply chain management is systematic and data-driven. We provide unparalleled support to our veterinary distributors, assisting with document and product registration, supply chain coordination and market share growth.
Uses
What is Fosfomycin used for?
It's used to treat bacterial infections such as:
- infectious coryza
- fowl cholera
- fowl typhoid
- colibacillosis
- salmonellosis
- ORT (Ornithobacterium Rhinotracheale Infection)
- CRD (Chronic Respiratory Disease)
What animals can be treated with Fosfomycin Oral Solution?
This medicine is recommended for poultry, chicken, ducks and geese.
How is a Fosfomycin Oral Solution used?
This medicine has been manufactured as a liquid, which is intended to be administered orally.
Why is Fosfomycin Oral Solution used mainly for poultry?
This drug is primarily used for poultry because it has been found to be effective against the bacterial pathogens commonly found in these birds. Poultry, including chickens, turkeys, ducks, and geese, are often raised in high-density environments, making them more susceptible to contagious diseases. While Fosfomycin serves poultry well, other antibiotics or treatments may be more suitable and effective for the health of other animals.
Can Fosfomycin be used to prevent bacterial infections in poultry, or is it only for treatment?
It can be used for both the treatment and prevention of bacterial infections in poultry.
Can Fosfomycin Oral Solution be used in backyard or hobbyist poultry flocks?
Fosfomycin is not limited to large-scale poultry farming and can also be used in smaller backyard or hobbyist use. Owners must work closely with a veterinarian to ensure the responsible use of the medication.
Is Fosfomycin Oral Solution available over the counter, or does it require a veterinarian's prescription?
The drug is typically a prescription medication and should be administered under the guidance of a veterinarian.
Can Fosfomycin Oral Solution be used in pregnant or lactating poultry?
Its use in pregnant or lactating poultry should be approached with caution. Consult a veterinarian to assess the potential risks and benefits, as effects can vary depending the stage of pregnancy or lactation.
What is the withdrawal period for Fosfomycin?
There is a withdrawal time of 10 days for meat and 5 days for eggs.
Can Fosfomycin Oral Solution be mixed with other medications or supplements?
Care should be taken when combining fosfomycin with other medications or supplements. Always consult with a veterinarian before mixing fosfomycin with other treatments.
Can Fosfomycin Oral Solution be used in conjunction with vaccines?
Fosfomycin can be used alongside vaccination programs in poultry farming. Vaccination helps prevent certain diseases, while Fosfomycin can be used for treatment and prevention of bacterial infections. As always, seek veterinary guidance before starting any regimen on animals.
Is Fosfomycin Oral Solution effective against all strains of bacteria in poultry?
While fosfomycin is a broad-spectrum antibiotic and effective against many strains of bacteria, it may not be effective against all types. Some bacteria can develop resistance to antibiotics, so it's important to have a bacterial culture and sensitivity test done before starting.
How long does it take for the drug to show results in poultry?
The time frame for seeing results from fosfomycin treatment can vary based on the severity of the infection and the overall health of the poultry. In some cases, improvement might be noticeable within a few days. The full course of treatment should still be completed as prescribed even if the animal is already showing signs of improvement.
Is Fosfomycin Oral Solution effective against viral infections in poultry?
Fosfomycin is an antibiotic specifically designed to target bacterial infections. It does not have antiviral properties.
What should be done if poultry show no improvement or worsen during Fosfomycin treatment?
If the animal does not show improvement or its condition worsens, contact a veterinarian promptly. This can be an indication of antibiotic resistance or an underlying issue that requires a different treatment approach.
How should Fosfomycin Oral Solution be stored?
This medication should be stored in a dark, dry location under 30°C. The bottle should be sealed tightly when not in use.
Dosage
How much Fosfomycin Oral Solution should be given to poultry?
The usual dose is 10mg of fosfomycin per kg of body weight. The duration of treatment should be 3-5 consecutive days.
Can Fosfomycin Oral Solution be used in all age groups of poultry?
It can be used in different age groups, including chicks and adult birds, but the dosage and administration might vary depending on the age and weight.
What should be done in case of accidental Fosfomycin Oral Solution overdose?
Stop giving the medication right away and seek assistance from an avian specialist or veterinarian. While awaiting help, closely observe the birds for any signs of adverse effects, such as changes in behavior, appetite, or water consumption, and report these observations.
What should be done if a dose of Fosfomycin Oral Solution is missed?
Administer the medication as soon as possible; if it is close to the time for the next scheduled dose, skip the missed dose and continue with the regular schedule.
Refer to a veterinary doctor or pharmacist for guidelines on dosage.
Side Effects
As with all pharmaceuticals, some unwanted effects can occur from the use of Fosfomycin Oral Solution.
Common side effects that have been reported include occasional digestive disturbances such as diarrhea or a decrease in feed intake. However, these are generally rare and not severe.
Very few side effects have been recorded when administered at the recommended dosages. Fosfomycin is generally considered safe and well-tolerated with a low rate of adverse effects.
For a comprehensive list of all possible side effects of this medication, consult a veterinarian for more detailed guidance.
Precautions
Do NOT use Fosfomycin Oral Solution for an animal that: • has a known allergy or hypersensitivity to any of the ingredients.
A high mineral salt concentration will interfere with the solubility of fosfomycin. When the drug is administered orally to animals, it needs to be dissolved in water to ensure proper delivery and absorption. However, when the water source contains a high concentration of mineral salts, these salts can bind to the drug's molecules, forming insoluble complexes that are less bioavailable. This reduced solubility can hinder the medication's effectiveness in treating bacterial infections.
What are the most common animals Fosfomycin Oral Solution is used for?
Fosfomycin Oral Solution is commonly used in poultry, including:
- Broiler Chickens: This type of poultry is often prone to bacterial infections. To combat these, fosfomycin is administered orally in drinking water at a dose of 150 pg/mL for five consecutive days. The drug helps ensure healthy growth of the birds by effectively treating these infections.
- Turkeys: Although less common than in broiler chickens, fosfomycin can also be used in turkeys to treat various infectious diseases. Like in chickens, the drug is administered orally, aiding in the prevention and treatment of disease to promote healthy growth.
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Why AdvaCare Pharma?
As an industry leader, we are aware of our responsibility to provide affordable and sustainable solutions to improve healthcare worldwide.