Enrofloxacin + Bromhexine HCl Oral Solution (100ml bottle, 500ml bottle and 1L bottle)
Enrofloxacin + Bromhexine HCl Oral Solution (1 bottle)
Enrofloxacin + Bromhexine HCl Oral Solution (100ml bottle, 500ml bottle and 1L bottle)
Enrofloxacin + Bromhexine HCl Oral Solution (1 bottle)
*Packaging color and/or animals may vary according to distribution region.

Enrofloxacin + Bromhexine HCl Oral Solution

EnbroCare™
Enrofloxacin + Bromhexine HCl Oral Solution is a combination medicine used to treat bacterial infections with cough in poultry. This oral solution has been manufactured by AdvaCare Pharma, a global manufacturer and supplier of GMP/ISO-certified veterinary products.

Dosage

Packaging

What is Enrofloxacin + Bromhexine HCl?

Therapeutic Class:
Target Species:

Active Ingredients: Enrofloxacin + Bromhexine HCl

Enrofloxacin + Bromhexine HCl Oral Solution is a combination drug used to treat certain bacterial infections and control coughing in poultry. It is indicated for the treatment of respiratory tract infections that are present with sputum, including bronchitis and emphysema.

This medication combines two active ingredients, an antibiotic and a mucolytic agent.

Enrofloxacin belongs to the family of medicines called fluoroquinolone antibiotics. It works by inhibiting DNA synthesis. Enrofloxacin displays bactericidal activity against a wide range of bacteria, including Staphylococcus, Escherichia coli, Proteus, and Klebsiella. This drug is well absorbed when taken orally and reaches peak plasma concentrations within 1 to 2 hours in poultry. It is widely distributed and reaches the respiratory tissues. It is partially metabolized in the liver to ciprofloxacin which also has antibacterial activity. It is secreted through the kidneys by glomerular filtration and tubular secretion. It inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication and transcription. This leads to the bactericidal effect.

Bromhexine is classified as a mucolytic. It works by breaking down mucus. This compound is also rapidly absorbed from the gastrointestinal tract after oral administration and it is distributed in the lungs. It is metabolized by the liver and excreted by the kidneys. It increases the production of serous mucus in the respiratory tract, by making the phlegm less viscous and promoting its expectoration.

Enrofloxacin has an antibacterial action, while Bromhexine has a mucolytic effect.

It is important to note that Enrofloxacin + Bromhexine HCl Oral Solution is for veterinary purposes only.

AdvaCare Pharma is a manufacturer and worldwide exporter of Enrofloxacin + Bromhexine HCl Oral Solution. We offer a broad range of competitively priced veterinary medications available for global distribution. Our livestock medicines are produced in our GMP-certified facilities in China, India, and the USA.

Why are we a quality Enrofloxacin + Bromhexine Oral Solution manufacturer?

AdvaCare Pharma, an American company, is a quality manufacturer of Enrofloxacin + Bromhexine Oral Solution for veterinary use. We are committed to the manufacture and global distribution of over 250 GMP-certified veterinary medicines, including 70+ oral liquid formulations.

As a trusted Enrofloxacin + Bromhexine manufacturer, our approach to supply chain management is systematic and data-driven. We provide unparalleled support to our veterinary distributors, assisting with document and product registration, supply chain coordination and market share growth.

Uses

What is Enrofloxacin + Bromhexine used for?

It is used to treat respiratory infections such as bronchitis and fowl cholera.

What animals can be treated with Enrofloxacin + Bromhexine Oral Solution?

This medicine is recommended for poultry.

How is Enrofloxacin + Bromhexine Oral Solution used?

This medicine has been manufactured as a liquid, which is intended to be administered orally.

Whenever the Solution is mixed with feed, the product should be used immediately. Medicated drinking water should be used within 24 hours.

How does Bromhexine HCl from this product help in treating respiratory infections in poultry?

This compound is a mucolytic agent that helps in breaking down the thin mucus from the respiratory tract of the animal. It helps in expelling it from the respiratory tract. It aids in managing respiratory conditions that lead to excessive mucus production. It also improves the efficacy of the Enrofloxacin from this antibiotic and provides better airway clearance.

How does Enrofloxacin from this product help in treating respiratory infections in poultry?

It aids by inhibiting the bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription, repair, and recombination. This contributes to cell death and this antibiotic has a bactericidal effect. It is efficient in treating both gram-negative and gram-positive bacteria depending on the susceptibility of the bacteria. This product is mainly used for treating respiratory infections in poultry.

How can Enrofloxacin + Bromhexine Oral Solution help in cases of fowl cholera?

This is a contagious bactericidal disease that is caused by Pasteurella multocida. This drug can clear the airway of the animal and can have a bactericidal effect on the pathogen. It can reduce clinical signs like fever, appetite loss, ruffled feathers, mucous discharge, respiratory difficulty, and green watery diarrhea.

To achieve good results in the treatment process, farms should have good management practices including a high level of biosecurity. Affected animals should be excluded from the poultry houses and proper disinfectants should be used. Live attenuated vaccines can also help in the prevention of the disease.

Is only Enrofloxacin + Bromhexine Oral Solution enough for fowl cholera in poultry?

No, only this drug cannot help in the complete eradication of the disease. Depopulation, through cleaning, and disinfection is also needed. Good biosecurity, vaccination, and prompt usage of antimicrobials is also recommended.

Is only Enrofloxacin + Bromhexine Oral Solution enough to treat a respiratory infection in poultry?

Enrofloxacin is a broad-spectrum antibiotic that can help in treating many bacterial infections and Bromhexine HCl is a mucolytic that helps in clearing the respiratory secretions. However, the efficacy of this drug depends on the present pathogen because antibiotics are only effective against bacteria. For treating viruses or fungi other drugs are needed.

Additional antibiotics, vitamins, and other drugs might be needed depending on the severity of the health issue. Bacterial resistance to this antibiotic can also lead to unsuccessful treatment and veterinarians need to observe the treatment process to determine whether this drug is the right choice.

Environmental factors like ventilation, high ammonia levels, and other stressors can also slow down the healing process. Before prescribing this antibiotic, veterinarians should also advise the farmers about proper practices.

Can Enrofloxacin + Bromhexine Oral Solution interact with other drugs?

Yes, this drug might interact with other drugs. This includes antacids, antibiotics, corticosteroids, iron, zinc, levothyroxine, mycophenolate mofetil, methotrexate, nitrofurantoin, probenecid, quinidine, sildenafil, sucralfate, theophylline, and warfarin. Farmers should inform the veterinarian about any drugs they are giving to the animals at the moment and decide whether this drug is suitable for them.

Is Enrofloxacin + Bromhexine Oral Solution efficient in treating viral diseases?

This medication helps in treating bacterial infections that lead to respiratory issues. Bromhexine from this product can improve the breathing process and clear the airways of the animals, but Enrofloxacin is not effective against the viral pathogen. For treating viral diseases, antiviral drugs, vitamins, and other supplements might help.

What should be done if a dose of Enrofloxacin Oral Solution is missed?

Administer the medication promptly. If it is nearing the time for the next scheduled dose, skip the missed one and resume the regular schedule. If several doses are missed, please consult a veterinarian. It is important to adhere to specific and predetermined time schedules for antibiotics to prevent potential side effects.

How should Enrofloxacin + Bromhexine Oral Solution be stored?

This medication should be stored in a dark, dry location under 30°C.

Is there a withdrawal period after treatment with Enrofloxacin + Bromhexine?

The withdrawal time is 7 days. The exact duration will depend on local regulations.

Dosage

How much Enrofloxacin + Bromhexine Oral Solution should be given to poultry?

The usual dose is 0.25ml per 1 liter of drinking water. The duration of treatment is 3-5 days.

Refer to a veterinary doctor or pharmacist for guidelines on dosage.

Side Effects

As with all pharmaceuticals, some unwanted effects can occur from the use of Enrofloxacin + Bromhexine Oral Solution.

Some common side effects may include but are not limited to: • gastrointestinal effects at higher doses

Serious side effects may include:

  • allergic reaction
  • uncoordinated walking
  • seizures
  • depression
  • lethargy
  • urinary crystals
  • vision changes in cats

For a comprehensive list of all possible side effects of this medication, consult a veterinarian.

Precautions

Do NOT use Enrofloxacin + Bromhexine Oral Solution for an animal that:

  • has a known allergy or hypersensitivity to any of the ingredients.
  • is dehydrated.

Treatment with this drug should be administered with caution if an animal:

  • is pregnant or lactating.
  • has kidney or liver disease.
  • has a seizure disorder.

There are many known interactions between enrofloxacin and other drugs, including antacids, antibiotics, corticosteroids, iron, zinc, levothyroxine, mycophenolate mofetil, methotrexate, nitrofurantoin, probenecid, quinidine, sildenafil, sucralfate, theophylline, and warfarin.

This drug may affect the results of a liver enzyme blood work test.

Maintain proper hygiene practices when administering this supplement.

If a dose is missed, avoid administering double doses.

This drug should be kept out of reach of children. It is only for animal treatment.

What are the most common animals Enrofloxacin + Bromhexine HCl Oral Solution is used for?

Enrofloxacin + Bromhexine HCl Oral Solution is mainly used for treating infections caused by susceptible microorganisms. This includes treatment of the following:

  • Mycoplasma spp.
  • E. coli
  • Pasteurella multocida
  • Salmonella

Poultry Bacterial Infections

This drug is used in poultry for treating various respiratory infections and diseases. It is also used to treat enteric and systemic infections. Bromhexine HCl from this product helps in managing excessive mucus production and helps in clearing the airways. It is also used to enhance the effectiveness of the antibiotic from this product. It is used in treating Chronic Respiratory Disease (CRD) caused by Mycoplasma spp.

Veterinarians should decide whether the drug is appropriate for the animal’s current health condition.

*Regulatory compliance may vary according to production standard, import requirements and/or manufacturing origin.
Sandra Tashkovska Profile
Medically reviewed by Sandra Tashkovska, DVM
October 14, 2024

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