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Ferrous Sulfate + Folic Acid Tablets
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What is Ferrous Sulfate + Folic Acid?
Active Ingredients: Ferrous Sulfate, Folic Acid
Ferrous Sulfate + Folic Acid Tablets are a supplement used to treat or prevent anemia caused by iron or folate deficiency, which is very common among women during adolescence and childbearing age.
Ferrous sulfate is a type of iron that is easily absorbed in the body. Iron is necessary to produce red blood cells. This compound renews the iron stores in the body which are necessary for hemoglobin production. Hemoglobin carries the oxygen from the lungs to tissues and it is a critical component of hemoglobin. This product when ingested orally is absorbed in the duodenum and upper jejunum. It is then transported in the blood and it is bound to transferrin. It is either utilized for hemoglobin synthesis, stored in ferritin and hemosiderin complexes, or excreted via sloughed intestinal cells, sweat, and urine.
Folic acid aids in the production and maintenance of new cells in the body. It may also help to prevent DNA changes that may lead to cancer. It helps in red blood cell production and the proper development of the fetal nervous system during pregnancy. This compound is absorbed in the upper part of the small intestine and then it undergoes a conversion to its active form, tetrahydrofolate. This active form is involved in the nucleotide synthesis and amino acid metabolism.
AdvaCare Pharma's Ferrous Sulfate + Folic Acid Tablets are manufactured in GMP-certified factories located in China, India, and the USA. We routinely inspect our production facilities to ensure our products meet health, safety, and environmental standards.
Why are we a trusted Ferrous Sulfate + Folic Acid Tablets manufacturer?
Ferrous Sulfate + Folic Acid Tablets are distributed by AdvaCare Pharma, an American-owned and operated company.
We are committed to creating sustainable and cost-effective pharmaceutical products to improve access to healthcare solutions worldwide. We are proud to work with a variety of international partners, including distributors, hospitals, pharmacies, and many other institutions.
Uses
What is Ferrous Sulfate + Folic Acid used for?
It is used to treat or prevent iron deficiency anemia (low iron levels) that may be caused by pregnancy.
How should Ferrous Sulfate + Folic Acid Tablets be used?
This medication is intended to be taken orally.
What dose should be taken?
The usual dose for adults is 1 tablet taken once a day.
There are no defined dosage guidelines for pediatric and geriatric patients. There are also no defined dosages for people with liver or renal impairments. Consult a doctor to get personalized advice based on your current health condition.
Refer to a doctor or pharmacist for guidelines on dosage. Do not exceed what they advise.
Who can take Ferrous Sulfate + Folic Acid Tablets?
This product can be taken by anyone with suboptimal nutritional status. It is most often used to treat or prevent iron deficiency anemia that is caused by anemia or pregnancy.
Are Ferrous Sulfate + Folic Acid Tablets safe for pregnant women?
Yes, this product is safe for pregnant women, but pregnant women should consult with a doctor before taking them. They should also inform their healthcare providers about any prescribed or unprescribed drugs they are taking at the moment so they can avoid an overdose if they take supplements containing ferrous sulfate and folic acid.
Are Ferrous Sulfate + Folic Acid Tablets safe for pediatric patients?
These tablets are generally considered safe for pediatric patients who are able to swallow the drug in the form of a tablet. Children should be carefully examined before prescribing them any drugs or supplements and the prescribing should be based on their current health status.
Other warnings
This product should not be taken 2 hours after taking oral tetracycline antibiotics because the antibiotics can interfere with this supplement.
In cases of overdose, the most common side effects are gastrointestinal problems like discomfort, nausea, constipation, or diarrhea. If patients experience these symptoms, they should seek immediate medical help.
Consult with a doctor if you are pregnant or planning to get pregnant before taking this product.
This supplement can decrease the absorption of drugs like bisphosphonates (for example, alendronate), levodopa, penicillamine, quinolone antibiotics (for example, ciprofloxacin, levofloxacin), thyroid medications (for example, levothyroxine), and tetracycline antibiotics (for example, doxycycline, minocycline).
Avoid using these tablets at the same time as antacids. Antacids should be taken at least 2 hours between taking this medication.
These tablets may interfere with some lab tests like stool occult blood tests and might lead to false test results. If you are using this supplement, you should notify your doctor or the lab personnel.
Side Effects
As with all pharmaceuticals, some unwanted effects can occur from the use of Ferrous Sulfate + Folic Acid Tablets.
Common side effects include, but may not be limited to:
- diarrhea or constipation
- nausea or vomiting
- heartburn
- darkened urine color
Serious side effects may include:
- trouble breathing or swallowing
- severe abdominal pain
- bloody stools
For a comprehensive understanding of all potential side effects, consult a medical professional.
If any symptoms persist or worsen, or you notice any other symptoms, please call your doctor immediately.
Precautions
Do NOT use Ferrous Sulfate + Folic Acid Tablets if:
- You are allergic to any of the ingredients.
- You have iron overload syndrome.
- You have hemolytic anemia, porphyria, or thalassemia.
- You have regular blood transfusions.
Before treatment, consult your doctor regarding any medications you are taking to address potential drug interactions. Before you take this drug also tell your doctor or pharmacists about any products you are allergic to.
This medication may not be suitable for people with certain conditions, so it is important to consult with a doctor if you have any health conditions. Patients should inform their doctor especially if they have an iron overload disorder including hemochromatosis and hemosiderosis. They should also inform them about any liver or stomach problems.
Patients should inform their doctor or pharmacist if they have pernicious anemia (vitamin B12 deficiency) before start using this supplement. Folic acid can lead to misleading results in certain laboratory tests for vitamin B12 deficiency without solving the underlying anemia. Untreated vitamin B12 deficiency can cause severe nerve issues, such as peripheral neuropathy symptoms like numbness, pain, or tingling sensations.
This product during pregnancy and breastfeeding should be used only if the doctor advises based on the current health coondition of the patient.
References
Comparison of ferrous sulfate and ferrous glycinate chelate for the treatment of iron deficiency anemia in gastrectomized patients
Postgastrectomy iron deficiency anemia occurs in 20-50% of patients. The goal of this controlled experimental study is to compare the effects of ferrous sulfate and ferrous glycinate chelate in the treatment of anemia and to evaluate the presence of side effects. It included 18 gastrectomized patients with iron deficiency anemia.
The included patients were separated into two groups: group 1 received ferrous sulfate (200mg twice a day, corresponding to 80mg of elemental iron), and group 2 received ferrous glycinate chelate (250mg/d, corresponding to 50mg of elemental iron) for 4 months. Laboratory measurements were performed at the beginning of the study, and also after 2 and 4 months. Group 1 had improvements in their laboratory parameters after 4 months of treatment. This included increases in medium corpuscular hemoglobin (P = 0.02), serum iron (P = 0.02), ferritin (P = 0.04), and also a decrease in transferrin (P = 0.002). Ferritin levels increased above 20μg/L in seven patients using ferrous sulfate, and this occurred in only one patient using ferrous glycinate by the end of the study.
The findings from this research indicate that patients with iron deficiency anemia after gastrectomy treated with ferrous sulfate had better results in hematologic laboratory parameters than the ones treated with ferrous glycinate chelate.
Weekly Iron and Folic Acid Supplementation with Counseling Reduces Anemia in Adolescent Girls: A Large-Scale Effectiveness Study in Uttar Pradesh, India
This research assesses the effectiveness of weekly iron-folic acid supplementation in a large-scale project in reducing the prevalence of anemia in adolescent girls.
The patients from this study received weekly iron-folic acid tablets, family life education, and deworming tablets every 6 months. It included 150,700 adolescent school girls and non-schoolgirls of a total district population of 3,647,834.
Hemoglobin levels were measured in a randomly selected group of non-schoolgirls at 6 and 12 months, and in schoolgirls at 6 months. The study examined how supplementation influenced the prevalence of anemia and compliance rates over a period of 4 years.
Over the period of 4 years, the prevalence of anemia decreased from 73.3% to 25.4%. Big changes in hemoglobin levels and anemia prevalence were evident in the 6th month. There was no noticeable difference in the effects on hemoglobin levels or anemia prevalence between girls who received supervision and those who did not. Counseling emphasizing the benefits of consistent weekly intake of iron and folic acid contributed to a high compliance rate that exceeded 85%. The implementation cost was US$0.36 per beneficiary per year.
The conclusion of this research is that weekly iron-folic acid supplementation in combination with monthly educational sessions and deworming every 6 months effectively reduces anemia prevalence among adolescent girls in a cost-efficient manner. Adequate counseling is also essential for achieving good results.
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