*Packaging color may differ according to distribution region.

Digoxin Injection

DixinCare™

Digoxin Injection is a calcium channel blocker medication for parenteral use. At AdvaCare Pharma, we manufacture this pharmaceutical drug in our ISO/GMP-certified facilities with an emphasis on safety, quality, and procedure.

Dosage

Packaging

What is Digoxin?

Therapeutic Class:

Cardiovascular System

Active Ingredients: Digoxin

Digoxin Injection is an antiarrhythmic drug used to treat heart failure in adults and children. This medication may be used alone or in combination with other drugs, such as a diuretic or an ACE inhibitor. Digoxin is also used to treat certain types of abnormal heartbeat, such as atrial fibrillation, in adults.

Digoxin is classified in the drug class called antiarrhythmics (antidysrhythmics) or inotropic agents. It is a chemical derived from the digitalis plant. The active ingredient works by inhibiting sodium-potassium ATPase within the heart.

AdvaCare Pharma is a trusted global supplier of this medication. We offer a wide range of high-quality and cost-effective medical supplies that are available for distribution. Digoxin Injection is manufactured in GMP-certified facilities located in China, India, and the USA. These factories are regularly audited to ensure they meet WHO's standards, rules, and regulations.

Why are we a leading Digoxin manufacturer?

AdvaCare Pharma is a leading manufacturer of Digoxin Injection. To ensure the quality of our pharmaceutical products, we adhere to stringent GMP guidelines at our manufacturing facilities. We partner with distributors, hospitals, pharmacies, NGOs, and government institutions across over 45 markets worldwide, and our track record over the past two decades demonstrates that AdvaCare Pharma is a reliable supplier dedicated to high-quality and efficacious products.

Uses

What is Digoxin used for?

It is used to treat heart failure and atrial fibrillation.

How is Digoxin Injection used?

This medication has been manufactured as a solution, which is intended to be injected intramuscularly or by intravenous infusion.

What dose should be given?

The usual dose for adults is 2.4-3.6mcg/kg, given once per day, IV/IM.

For pediatric patients:

over 10 years old: 2.4-3.6 mcg/kg per dose, given once per day.
between 5 to 10 years old: 4.6-9 mcg/kg per day, divided and given every 12 hours IM/IV.
between 2 to 5 years old: 7.6-10.6 mcg/kg per day, divided and given every 12 hours IM/IV.
between 1 month to 2 years old: 9-13 mcg/kg per day, divided and given every 12 hours IM/IV.
neonates (full-term): 6-9 mcg/kg per day, divided and given every 12 hours IM/IV.
neonates (premature): 3.8-6.2 mcg/kg per day, divided and given every 12 hours IM/IV.

Side Effects

As with all pharmaceuticals, some unwanted effects can occur from the use of Digoxin Injection.

Common side effects include, but may not be limited to:

nausea or diarrhea
dizziness or weakness
headache
rash

Seek medical attention if the following develop:

gastrointestinal effects (nausea, vomiting, diarrhea, abdominal pain)
changes in heart rate
lightheadedness
tarry stools
mood or mental changes (such as confusion or hallucinations)
breast tenderness
changes in vision

For a comprehensive list of all side effects, consult a doctor or pharmacist.

If any symptom persists or gets worse, or any new symptoms appear, please call your doctor.

Precautions

Do NOT use Digoxin Injection if:

You are allergic or hypersensitive to any of the ingredients.
You have ventricular fibrillation.
You are being treated with bretylium or calcium chloride.

This medication may not be suitable for people with certain conditions, including:

sick sinus syndrome or AV block (without pacemaker)
past heart attack
bradycardia that has caused fainting
Wolff-Parkinson-White Syndrome
renal disease
electrolyte imbalances
thyroid disease
recent gastrointestinal illness with vomiting or diarrhea

This medicine should only be used during pregnancy and breastfeeding if the benefits outweigh the risks. Consult a doctor or healthcare professional before treatment.

Many drugs are known to interact with Digoxin, such as brigatinib, calcium gluconate, ceritinib, crizotinib, dronedarone, ozanimod, and succinylcholine. This not a complete list of interactions, so please consult with a healthcare professional before treatment.

During treatment with Digoxin, it is important to check blood pressure and heart rate daily. It may be necessary to have regular blood tests and to check kidney function.

*Regulatory compliance may vary according to production standard, import requirements and/or manufacturing origin.